‘Shuddh Desi Romance’ is the story about the hair-raising minefield between love, attraction and commitment. It starts off with Raghu Ram (Sushant Singh Rajput), a tourist guide in Jaipur who doubles up as a rental baraati for Goyal (Rishi Kapoor), a wedding planner. Raghu is experiencing pre-marital jitters before his arranged marriage. Goyal has hired a fake baraat to accompany Raghu to his wedding which includes Gayatri (Parineeti Chopra), an open minded, independent woman who lives life on her own terms. On the way to his wedding venue, Raghu falls for Gayatri. A confused Raghu, heavily impressed by her freedom, gathers the guts to run away from his own wedding.
A fortnight later, the two begin dating and eventually enter into a live-in relationship. In India, such relationships can be socially frowned upon, so they hide the relationship from their neighbours by pretending to be siblings. Mr. Gupta (Tarun Vyas), a neighbour of Gayatri, catches Raghu with Gayatri and tries to create distrust between them but the couple is able to reconcile and decide to get married. However on the day of the wedding, Gayatri runs out on him, and Raghu is left inconsolable.
Soon after, at a wedding, Raghu meets Tara (Vaani Kapoor), the woman he was going to marry before he met Gayatri. She asks him out initially on a revenge trip but slowly falls for him. Just as Raghu is about to ask her to marry him at a wedding, he runs into Gayatri. The bride's mom sends Raghu and Gayatri to pick up the priest from the station. On the way, Gayatri tries to talk to Raghu but he is reluctant. Later at dinner, Raghu finds Tara and Gayatri sitting on the same table. Tara tells him that she invited Gayatri to dinner on Sunday. Raghu gingerly makes an excuse for the bathroom. Gayatri follows him and they both confess their love for each other. Tara arrives and catches them in a loving embrace. Tara leaves while Raghu and Gayatri are compelled by Goyal to accept that they love each other and that they should marry.
Three days later, on the night of their marriage, Gayatri and Raghu run into each other at the main gate while both are trying to run away. Later they meet at Gayatri's home where Raghu says that he truly loves Gayatri but he doesn't want to be imprisoned by marriage. They agree to resume their live-in relationship.
Shuddh Desi Romance is basically the Indian interpretation of Julia Roberts's Runaway Bride. The stories are different but the central idea is the same: what happens when someone loves falling in love but panics at the idea of getting married!