The story is about Lily Lele and Laila Lele (Both played by Sunny Leone), twins sisters who organise the centre to those people who are 'Sex Addict'. Sunny Kele (Tusshar Kapoor) and Aditya Chothia (Vir Das) are two spoilt brats who are sex-addict, meets the twins sisters and falls in love with each. Deshdrohi and Deshpremi (Both played by Shaad Randhawa) are two look-alikes, Deshpremi is physically disabled and Deshdrohi is a womaniser. Lily and Deshpremi are about to get married.

The story revolves around the various twists and funny chaos in their lives. It starts off with the 'sparkling' introduction of Riteish Deshmukh, a self-confessed 'mastizaada'. Seeing his antics and his magnetism towards the opposite sex makes the two self-confessed sex maniacs Aditya Chotiya and Sunny Kele to become his disciples! While Aditya and Sunny get thrown out of an ad agency owned by Vivek Vaswani because of their extremely sexual content in all their ads, they land up starting their own ad agency named 'XXX'. On the other hand, in order to find a solution for their sexual obsessions, they check into a rehabilitation centre that's run by the twin sisters (who are sex addicts themselves) Laila Lele and Lilly Lele.

While Laila Lele is modernity personified, Lilly Lele is a girl with simple values, but, stammers while talking. A lucky draw in the rehab centre wins Aditya and Sunny a trip to Pattaya along with Laila and Lily. Amidst all this, Aditya and Sunny land up falling in love with Laila and Lilly respectively. The problem is that Lilly Lele is already engaged to Deshpremi (Shaad Randhawa), a wheelchair-bound wannabe army man who finds it tough to 'stand' on his feet. Amidst all this, there also exists 'Son-Das' (Suresh Menon), who happens to be the 'stereotypical gay' brother of Lilly and Laila. Situations go topsy-turvy when he starts developing feelings towards Sunny Kele. A series of funny moments follow the story and finally Sunny and Aditya marries their beloved, Laila and Lily.