‘Hum Hai Raahi Car Ke’ is about two friends, who take an impromptu road trip to Pune, which doesn't turn out as planned. The film begins well with a gawky call center executive Priyanka (Adah Sharma) answering weird medical queries over the phone. She even warns a client that ‘beauty creams’ is for external use only. The scene evokes laughter, thus making you believe the film could turn out to be a fun comedy.

Unfortunately, within few minutes, you realize the film has no story in the first place. You see Priyanka's bachelor neighbour-cum-best friend Shammy (Dev Goel) loitering around in his house in colourful underwear. He even sniffs one of his underpants, thankfully, when he isn't wearing it!

The hyper-enthusiastic, forever-smiling Shammi (much to your annoyance) all of a sudden decides to attend a wedding in Pune and convinces Priyanka to accompany him. On the New Year's Eve they decide to travel from Mumbai to Pune. But a trip that should only take a couple of hours ends up becoming an all-nighter, with events keeping them on the road and preventing them from reaching their destination. The film is all about what happens on that road trip.